HORIZON 2020 | Santé, Changement Démographique & Bien-être - HORIZON 2020 Tunisia
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Santé, HORIZON 2020 | Changement Dr Yosr Z. HAFFANI PCN Santé Démographique Faculté de Médecine de Sfax, Université de Sfax 23 Novembre 2017 & Bien-être
HORIZON 2020 = 3 PRIORITÉS EXCELLENCE LEADERSHIP INDUSTRIEL DEFIS SOCIETAUX SCIENTIFIQUE Répondre aux défis sociétaux Posi2onner l’UE comme Favoriser plus d’innova2on et de l’UE (vieillissement pôle d’Excellence renforcer le leadership démographique, changement scien2fique mondial industriel de l’UE dans le clima2que, sécurité, monde développement durable, …) 5
HORIZON 2020 EXCELLENCE PRIMAUTE SCIENTIFIQUE INDUSTRIELLE DEFIS SOCIETAUX ERC 13md€ Technologies clefs 13,6md 7,5md€ European Research génériques € Santé Council TIC, microélectronique, photonique, nanotechnologies, matériaux Bioéconomie 3,9md€ avancés, Systèmes de produc>on, biotechnologies Espace Energie 5,9md€ FET 6md€ Future Emerging 6,3md€ Technologies Transport Changement 3,1md€ Marie Curie 2,7md€ Accès au 616m€ financement à clima2que Infrastructures 2,5md€ risque Sociétés 1,3md€ Innova)on dans 2,8md€ inclusives les PME Sécurité 1,7md€ Diffusion de l’excellence et élargissement de la par2cipa2on (817m€) Ins2tut Européen d’Innova2on et Technologie (EIT) (2,7md€) Science pour et avec la société (462m€) Centre commun de recherche (JRC) Euratom 6
CONTEXTE DU DÉFI SANTÉ • Changement démographique • Accroissement du fardeau des maladies non-‐transmissibles/« lifestyle » • Augmenta2on du coût de la santé & de la pression sur les systèmes de santé • Augmenta2on des coûts du développement des médicaments, vaccins, disposi2fs médicaux… • Insuffisance d’évidences sur les avantages et l’efficacité, des approches et pra)ques actuelles à Promouvoir le vieillissement ac)f et en bonne santé à Favoriser une approche « tout au long de la vie » à volonté de « scale-‐up » la recherche et amplifier sur l’existant à Soutenir le transfert vers la clinique à Réduire les inégalités dans le domaine de la santé à U2lisa2on des infrastructures européennes
Main objectives: ‘Promoting healthy ageing and personalised healthcare'. BUDGET 2018 : 396 M€ 2019: 517 M€ 2020 : 490 M€ HEALTH 2014-2020 € 7.472 bil. The indicative budgets for the calls announced are listed in Work Programme.
RÈGLES DE PARTICIPATION DES DÉFIS • Toute entité légale peut participer • 3 entités légales de 3 Etats-membres ou Etats associés différents (exception pour outils PME - mono bénéficiaire et action de coordination) • Entités légales financées : établies dans les Etats-membres ou Etats associés + Exception unique du défi santé: USA financés • Pour les Etats tiers : certains « low-income » sont financés (cf liste ci-dessous ) – ou expressément prévu dans le programme de travail http://ec.europa.eu/research/participants/data/ref/h2020/grants_manual/hi/3cpart/h2020- hi-3cpart_en.pdf • Certains pays ont des programmes nationaux ( ex: Mexique, Australie, Canada, …) Des critères d’évaluation simples et uniformes Excellence – Impact – Mise en œuvre http://ec.europa.eu/research/participants/data/ref/h2020/wp/2014_2015/annexes/h2020- wp1415-annex-h-esacrit_en.pdf
NE PAS NÉGLIGER LES ASPECTS IMPORTANTS • Implica2on des PME • Aspect éthique (expérimenta2on humaine et animale ) • Aspect genre dans le projet et dans le consor2um • Implica2on des ONG, associa)ons de pa)ents et acteurs de la société civile • No2on de data management (+ open access et open data volontaire) (Data Management Plan are incited to iden>fy the exis>ng European research data infrastructures that may be used and how these may be mobilised, in par>cular for long-‐term data cura>on and preserva>on)
TYPE OF ACTIVITIES RIA-‐ Research and Innova)on Ac)ons 100% funding rate IA-‐ Innova)on Ac)ons 36-‐48 months 70% funding rate 2-‐5 mil. € 30-‐36 months Consor)um of min. 3 partners from 3 MS or AC 2-‐5 mil. € Consor)um of min. 3 partners from 3 MS or AC CSA-Coordination and Support Actions 100% funding rate 12-30 months 0.5 – 2 mil. € 1 legal entity
CALENDRIER PUBLICATION, SOUMISSION ET ÉVALUATION Work Programme 2018-‐2020 § Critères d’évalua2on: Il existe des seuils de passage Passage à 1 Etape RIA : Seuils : Excellence , Impact, Implementa2on = Total: 13/15 § « Time to Grant »: 8 mois (soumission -‐ résultat 5 mois -‐ phase de négo2a2on 3 mois)
OU TROUVER L ES CALLS? PARTICIPANT PORTAL HTTP://EC.EUROPA.EU/RESEARCH/PARTICIPANTS/PORTAL/DESKTOP/EN/OPPORTUNITIES/I NDEX.HTML
OU TROUVER L ES CALLS? PARTICIPANT PORTAL HTTP://EC.EUROPA.EU/RESEARCH/PARTICIPANTS/PORTAL/DESKTOP/EN/OPPORTUNITIES/I NDEX.HTML
DÉFI SANTE – WORK PROGRAMME 2018-2020 Better Health & Care, Economic Growth & Sustainable Health DG Research Technological Development RTD Digital transformation in Health and Care DG Communica)on Network Trusted digital solutions and Content & Technology Cybersecurity in Health and Care CNECT (TIC) IPr Inducement Prize
COMMENT LIRE UNE LIGNE D’APPEL? Area: Personalised Medicine Thème Date du call SC1-‐HCO-‐01-‐2018: Ac)ons in support of the Interna)onal Consor)um for Personalised Medicine [RTD] Titre et date du Specific challenge: call Popula2on cohorts are invaluable resources to obtain detailed descrip2on of individual biological varia)ons in connec)on with a variety of environmental, […] However, the lack of integra2on of these cohorts hampers the op)mal exploita)on of these resources, essen2al to underpin Défi spécifique à and facilitate the development of stra)fied and personalised medicine. relever jus)fica)on Scope: The proposals should aim at maximizing the exploita2on of cohorts by bringing together na2onal and/or European cohorts with common scien2fic Périmètre de […] European infrastructures and addi2onal collabora2ons with relevant interna2onal ini2a2ves are encouraged. Proposals should also engage with l’ac)on à relevant interna2onal/na2onal/regional authori2es to ensure that findings are implemented and translated into health policy. adresser The Commission considers that proposals reques2ng a contribu2on from the EU of between EUR 8 and 10 million would allow this specific Indica)on challenge to be addressed appropriately. Nonetheless, this does not preclude submission and selec2on of proposals reques2ng other amounts. Budget Expected impact: Expected impacts include one of or a combina2on of the following point(s): Impact •Contribute to providing novel informa2on on health maintenance, onset and course of diseases, or popula2on stra2fica2on, with a ajendu en view to tailor diagnosis or to op2mise treatment. lien avec le • Op2mise the use of popula2on cohorts in defining/improving clinical prac2ce and public health policy. défi • Make major conceptual, methodological and analy2cal contribu2ons towards integra2ve cohorts Type of ac)on: RIA Type de projet
DOSSIER DE CANDIDATURE : CONTENU WORK PROGRAMME 2018-2020 1- Excellence 3- Implémentation -Objectifs -Programme de travail -Relations avec le -Management (structure et programme de travail procédures) -Concept et approche -Le consortium dans son -Ambition ensemble -Les ressources 2- Impact 4 – Le consortium -Impacts attendus -Participants -Mesures pour -Tierce-parties maximiser l’impact 5- Ethique et sécurité
CHAQUE W ORK P ACKAGE E ST D ÉCRIT E N D ÉTAIL FICHE WORK PACKAGE
ENCHAINEMENT LOGIQUE D’UNITÉS WORK PACKAGES 16
TROUVER DES PARTENAIRES Ø U)lisez d'abord VOTRE réseau • U)lisez les réseaux de spécialistes des projets européens § Le service de fisorhealth: www.fisorhealth.eu § Rapprochez vous des organismes/universités/CHU § Si vous cherchez des PME u2lisez les réseaux régionaux et via le PCN PME § Cordis portal: htp://cordis.europa.eu/ Trouver ce qui a été financé • Par)cipez aux évènements autour de Horizon2020 ou interna)onaux § Infodays § Brokerage event
MAIN RESEARCH PRIORITIES FOR 2018-2020 Call 1. – Better Health and Care, Economic Growth & Sustainable Health Systems 1.1 Personalised Medicine 1.2 Innovative health and care industry 1.3 Infectious diseases and improving global health 1.4. Innovative health and care systems - Integration of care 1.5 Decoding the role of the environment for health and well-being Call 2. – Digital transformation in Health and Care Call 3. – Trusted digital solutions and Cybersecurity in Health and Care
DÉFI SANTE – WP 2018-2020 Better Health and Care (BHC) Call 1. "Better Health and care, economic growth and sustainable health systems” 1.1 Personalised Medicine I SC1-BHC-03-2018: Exploiting research results and potential of the human microbiome for personalised prediction and prevention of disease RIA 13 & 14 M€ SC1-BHC-04-2018: Rare Disease Joint Programme Co-Fund COFUND (European Joint Programme) 50 M€ SC1-BHC-05-2018: International flagship collaboration with Canada for human data storage, integration and sharing for developing personalised medicine approaches RIA 6 M€ over 4 years
DÉFI SANTE – WP 2018-2020 Better Health and Care (BHC) Call 1. "Better Health and care, economic growth and sustainable health systems” 1.1 Personalised Medicine II SC1-BHC-01-2019: Understanding causative mechanisms in co-morbidities RIA 4 & 6 M€ SC1-BHC-02-2019: Systems approaches for the discovery of combinatorial therapies RIA 4 & 6 M€
DÉFI SANTE – WP 2018-2020 Better Health and Care (BHC) Call 1. "Better Health and care, economic growth and sustainable health systems” 1.1 Personalised Medicine III Coordination Activities SC1-HCO-01-2018-2019-2020: Actions in support of the International Consortium for Personalised Medicine CSA 1.5 & 2 M€ SC1-HCO-02-2018: Data integration and data-driven in-silico models for enabling personalised medicine - a European standardization framework CSA 1.5 & 2 M€ SC1-HCO-04-2018: ERA-NET to support the Joint Programming in Neurodegenerative Diseases strategic plan (JPND) ERA-NET Cofund 5 & 6 M€
DÉFI SANTE – WP 2018-2020 Better Health & Care (BHC) Call 1. "Better Health and Care, economic growth and sustainable health systems” 1.2 Innovative Health & Care Industry SC1-BHC-09-2018: Innovation platforms for advanced therapies of the future RIA 6-8 M€ SC1-HCO-05-2018: Strengthen Regulatory Sciences and support for successful regulatory Scientific Advice CSA 1-2 M€ SC1-BHC-07-2019: Regenerative medicine: from new insights to new applications RIA 6-8 M€ SC1-BHC-10-2019: Innovation Procurement: Next generation sequencing (NGS) for routine diagnosis RIA 12-15 M€
DÉFI SANTE – WP 2018-2020 Better Health and Care (BHC) Call 1. "Better Health and Care, economic growth and sustainable health systems” 1.3 Infectious diseases and improving global health I SC1-BHC-15-2018: New anti-infective agents for prevention and/or treatment of neglected infectious diseases (NID) RIA 5 -10 M€ SC1-BHC-16-2018: Global Alliance for Chronic Diseases (GACD) 1 RIA 1 - 3 M€ Focus on Hypertension/Diabete SC1-BHC-21-2018: Research on HIV and/or tuberculosis in patients with mono-, co-infections or comorbidities in the contest of fostering the collaboration with (alt. widening the participants to) Russia and other countries in the Central- and Eastern European region RIA 2 - 4 M€
DÉFI SANTE – WP 2018-2020 Better Health and Care (BHC) Call 1. "Better Health and Care, economic growth and sustainable health systems” 1.3 Infectious diseases and improving global health II Coordination Activities SC1-HCO-06-2018: Global Research Collaboration for Infectious Disease Preparedness (GloPID-R), Establishment of an International Network of Research Centres on Global Governance for Infectious Disease Preparedness CSA 1.5 - 2 M€ SC1-HCO-09-2018: Building international efforts on cohorts CSA 1.5 - 2 M€ SC1-HCO-10-2018: Coordinating European brain research and developing global initiatives CSA 1 - 2 M€ SC1-HCO-11-2018: Strategic collaboration in healthcare research and innovation between EU & China CSA 1.5 - 2 M€
DÉFI SANTE – WP 2018-2020 Better Health and Care (BHC) Call 1. "Better Health and Care, economic growth and sustainable health systems” 1.3 Infectious diseases and improving global health III SC1-BHC-13-2019: Preparedness research for (Re-) Emerging Infectious Diseases RIA 12-15 M€ SC1-BHC-14-2019: Stratified host-directed approaches to improve prevention &/or treatment of infectious diseases RIA 6-10 M€ SC1-BHC-18-2019: EU-CELAC collaboration for research on non-communicable diseases RIA 1-3 M€ SC1-BHC-19-2019: Implementation research for maternal and child health RIA 2-4 M€ SC1-HCO-08-2019: Creation of a European wide sustainable clinical research networks for infectious diseases CSA 2-3 M€
DÉFI SANTE – WP 2018-2020 Better Health and Care (BHC) Call 1. "Better Health and Care, economic growth and sustainable health systems” 1.4. Innovative health and care systems - Integration of care SC1-BHC-23-2018: Novel patient-centred approaches for survivorship, palliation & end-of-life care RIA 3-4M€ SC1-BHC-26-2018: HTA research to support evidence-based healthcare RIA 8-10M€ SC1-HCO-12-2018: Innovation in health care - towards using pre-commercial procurement & public procurement of innovative solutions in health care systems CSA 2-3M€ SC1-BHC-22-2019: Mental health in the workplace RIA 2-4M€ SC1-BHC-25-2019: Demonstration pilots for implementation of Personalised Medicine in health care RIA 15-20M€
DÉFI SANTE – WP 2018-2020 Better Health and Care (BHC) Call 1. "Better Health and Care, economic growth and sustainable health systems” 1.5 Decoding the role of the environment for health and well-being SC1-BHC-27-2018: Endocrine disrupters – research for better regulation and improved understanding of health effects RIA 4-6M€ SC1-HCO-13-2018: Setting the Priorities for the European Environment and Health Agenda CSA 1.5-2M€ SC1-BHC-28-2019: The Human Exposome Project: a toolbox for assessing and addressing the impact of environment and climate change on health RIA 8-12M€
DÉFI SANTE – WP 2020 EUR 490 million Better Health and Care (BHC) Call 1. "Better Health and Care, economic growth and sustainable health systems” 1.1 Personalised Medicine SC1-BHC-06-2020: Digital diagnostics – developing tools for clinical decisions integrating in vitro and in vivo diagnostics SC1-HCO-03-2020: Improving EU-13 participation in EU-supported health research programmes CSA 1.2 Innovative Health & Care Industry SC1-BHC-08-2020: New therapies for Non Communicable Diseases SC1-BHC-11-2020: New, animal-free regulatory test methods for human safety testing at the horizon of 2030 SC1-BHC-12-2020: Boosting the translation of results of health research into validated, innovative applications
DÉFI SANTE – WP 2020 EUR 490 million Better Health and Care (BHC) Call 1. "Better Health and Care, economic growth and sustainable health systems” 1.3 Infectious diseases and improving global health SC1-BHC-17-2020: Global Alliance for Chronic Diseases (GACD) 2 SC1-BHC-20-2020: Using pre-commercial procurements and public procurement of innovative solutions in health care systems to: - reduce the risk of hospital-acquired infections and/or - improve integrated care 1.4. Innovative health and care systems - Integration of care SC1-BHC-24-2020: Healthcare interventions for the management of the elderly multimorbid patient 1.5 Decoding the role of the environment for health and well-being SC1-BHC-29-2020: The Human Exposome Project: a toolbox for assessing and addressing the impact of environment and climate change on health
DÉFI SANTE – WP 2018-2020 IPr Inducement Prize Other Actions 2018-2019 Prize 1 (2019) – Horizon Prize on novel solutions to reduce the spread of AMR in the environment 2M€ Prize 3 (2019) – Exemplary application of personalised medicine approaches at a local or regional level 1M€ Prize 5 (2019) - Novel tool(s) to limit the use of test animals in biomedical sciences and safety testing – RTD – Inducement Prize 1M€ Prize 2 (2020) - Surgical care in resource-poor settings Prize 6 (2020) - Implantation of smart medical devices to (re-) establish neural &/or neuronal function
MERCI POUR VOTRE ATTENTION Dr. Yosr HAFFANI Maître-Assistante NCP Santé, Changement Démographique et Bien-être health@horizon2020tunisia.org 31
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